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  • 标题:Characterization of a model of dietary-induced hypertriglyceridemia in young, nonobese rats.
  • 本地全文:下载
  • 作者:G M Reaven ; T R Risser ; Y D Chen
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1979
  • 卷号:20
  • 期号:3
  • 页码:371-378
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Healthy, nonobese, young rats developed hypertriglyceridemia (mean triglyceride levels of 250 mg/dl) following consumption of a sucrose-lard diet. The hypertriglyceridemia was apparent three days after start of the diet and persisted throughout the 4-week experimental period. Body weight, liver weight, and serum glucose levels were similar in animals eating either the sucrose-lard diet or standard rat chow. On the other hand, serum free fatty acid levels were slightly increased and serum insulin levels were substantially increased in animals eating the sucrose-lard diet. Determination of very low density lipoprotein turnover revealed that total triglyceride secretion in rats eating the sucrose-lard diet was significantly (P
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