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  • 标题:Sterol synthesis. A simplified method for the synthesis of 32-oxygenated derivatives of 24,25-dihydrolanosterol.
  • 本地全文:下载
  • 作者:E J Parish ; G J Schroepfer
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1981
  • 卷号:22
  • 期号:5
  • 页码:859-868
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:A simplified method is described for the preparation of 14 alpha-hydroxymethyl-4,4-dimethyl-5 alpha-cholest-8-en-e beta-ol, 14 alpha-hydroxymethyl-4,4-dimethyl-5 alpha-cholest-7-en-3 beta-ol, and 14 alpha-hydroxymethyl-4,4-dimethyl-5-alpha-cholest-6-en-3 beta-ol from commercial lanosterol. This method represents a modification of the approach introduced by Fried and co-workers (Fried, J., J. W. Brown, and L. Borkenhagen. 1965. Tetrahedron Lett. 2499-2504).
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