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  • 标题:Evidence for a compartmentation of brain microsomal diacylglycerol.
  • 本地全文:下载
  • 作者:L Binaglia ; R Roberti ; A Vecchini
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1982
  • 卷号:23
  • 期号:7
  • 页码:955-961
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Phosphatidylcholine synthesis from CDP-[methyl-14C]choline and membrane-bound diacyl-[U-14C]-sn-glycerol, formed through the glycerol phosphate pathway, has been examined in vitro in rat brain microsomes. When labeled diacylglycerol was incubated in the presence of unlabeled CDP-choline, the rate of phospholipid labeling looked very different from that measured in incubations of unlabeled diacylglycerol with CDP-[methyl-14C]choline. Evidence is given that diacylglycerol formed through the glycerol phosphate pathway belongs to a metabolic pool separate from the bulk membrane diacylglycerol.
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