出版社：American Society for Biochemistry and Molecular Biology
摘要：A novel method for the synthesis of cholesteryl ethers is described. The mesylates of fatty alcohols were treated with the sodium salt of cholesterol in toluene at 80 degrees C in the presence of anhydrous dimethyl formamide. The hexyl, tetradecyl, and oleyl cholesteryl ethers were synthesized in yields varying between 55 and 70%. Tritiated cholesteryl oleyl ether was also synthesized in good chemical (45%) and radiochemical (45%) yields.
