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  • 标题:Cholesterol 26-hydroxylase activity of hamster liver mitochondria: isotope ratio analysis using deuterated 26-hydroxycholesterol.
  • 本地全文:下载
  • 作者:E Kok ; N B Javitt
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1990
  • 卷号:31
  • 期号:4
  • 页码:735-738
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Deuterated 26-hydroxycholesterol prepared from diosgenin by modifications of existing methods permitted the determination of mitochondrial cholesterol 26-hydroxylase using endogenous cholesterol as the substrate. Enzyme activity in a group of Syrian hamsters was found to be 10.3 +/- 3.7 pmol.min-1.mg protein-1.
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