文章基本信息
- 标题：Differential effects of saturated fatty acids on low density lipoprotein metabolism in the guinea pig.
- 本地全文：下载
- 作者：M L Fernandez ; E C Lin ; D J McNamara 等
- 期刊名称：JLR Papers In Press
- 印刷版ISSN：0022-2275
- 电子版ISSN：1539-7262
- 出版年度：1992
- 卷号：33
- 期号：12
- 页码：1833-1842
- 语种：English
- 出版社：American Society for Biochemistry and Molecular Biology
- 摘要：Studies have shown that dietary fat saturation affects guinea pig plasma low density lipoprotein (LDL) levels by altering both LDL receptor-mediated catabolism and flux rates of LDL (Fernandez et al. 1992. J. Lipid Res. 33: 97-109). The present studies investigated whether saturated fatty acids of varying chain lengths have differential effects on LDL metabolism. Guinea pigs were fed 15% (w/w, 35% calories) fat diets containing either palm kernel oil (PK), 52% lauric acid/18% myristic acid; palm oil (PO), 43% palmitic acid/4% stearic acid; or beef tallow (BT), 23% palmitic acid/14% stearic acid. Plasma LDL cholesterol levels were significantly higher for animals fed the PK diet (P
