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  • 标题:Associations of hepatic and lipoprotein lipase activities with changes in dietary composition and low density lipoprotein subclasses.
  • 本地全文:下载
  • 作者:H Campos ; D M Dreon ; R M Krauss
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1995
  • 卷号:36
  • 期号:3
  • 页码:462-472
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:To test whether lipoprotein lipase or hepatic lipase activities are associated with lipoprotein subclasses, and to assess the effects of dietary manipulations on these associations, enzyme activities were measured in postheparin plasma (75 U heparin/kg) from 43 healthy men who were randomly allocated to a low-fat (24% fat, 60% carbohydrate) and a high-fat (46% fat, 38% carbohydrate) diet for 6 weeks each in a cross-over design. The high-fat diet significantly increased both lipoprotein lipase (+20%, P = 0.02) and hepatic lipase (+8%, P = 0.007) activities. On both diets, hepatic lipase activity was significantly positively correlated (P
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