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  • 标题:Expression of a novel human apolipoprotein (apoC-IV) causes hypertriglyceridemia in transgenic mice.
  • 本地全文:下载
  • 作者:C M Allan ; J M Taylor
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1996
  • 卷号:37
  • 期号:7
  • 页码:1510-1518
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:The human apolipoprotein (apo) C-IV gene has been recently identified: it is closely linked to the promoter region of the apoC-II gene (Allan, C.M., D. Walker, J. Segrest, and J. M. Taylor. 1995. Genomics. 28: 291-300). To determine the effect of apoC-IV gene expression on lipoprotein metabolism, transgenic mice were generated using a human apoC-IV cDNA construct. Human apoC-IV was found associated with plasma lipoproteins (d
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