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  • 标题:Adaptation of cholesterol absorption after proximal resection of porcine small intestine.
  • 本地全文:下载
  • 作者:M Pakarinen ; T A Miettinen ; J Lauronen
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1996
  • 卷号:37
  • 期号:8
  • 页码:1766-1775
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Cholesterol absorption occurs primarily in the upper small intestine. Our aim was to assess absorption of cholesterol during ileal adaptation after proximal small intestinal resection. In vivo absorption and elimination of cholesterol, plasma cholesterol, cholesterol precursors, and plant sterols were related to intestinal morphology and transit 4 (n = 5), 8 (n = 5), and 14 (n = 5) weeks after a 75% proximal resection of porcine small intestine, and compared to preoperative (n = 5) and transected (n = 5) control animals. Fractional cholesterol absorption, the daily amount of cholesterol absorbed, plasma cholesterol, and plant sterol to cholesterol proportions were significantly (P
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