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  • 标题:Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins
  • 本地全文:下载
  • 作者:Kathleen S. Montine ; Casey N. Bassett ; Joyce J. Ou
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1998
  • 卷号:39
  • 期号:12
  • 页码:2443-2451
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:The major apolipoproteins (apo) on human cerebrospinal fluid lipoproteins are apoA-I and apoE. Given the association between inheritance of the ε4 allele of the apoE gene (APOE4) and increased susceptibility to Alzheimer's disease, we tested the hypothesis that cerebrospinal fluid apolipoproteins may be influenced by APOE genotype and Alzheimer's disease. Lipoprotein fractions (d —Montine, K. S., C. N. Bassett, J. J. Ou, W. R. Markesbery, L. L. Swift, and T. J. Montine. Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins. J. Lipid Res. 1998. 39: 2443–2451.
  • 关键词:ApoA-II ; ApoE-ApoA-II heterodimer ; apoA-I ; Alzheimer's disease
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