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  • 标题:Hypolipidemic mechanisms of pectin and psyllium in guinea pigs fed high fat–sucrose diets: alterations on hepatic cholesterol metabolism
  • 本地全文:下载
  • 作者:Marcela Vergara-Jimenez ; Karin Conde ; Sandra K. Erickson
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1998
  • 卷号:39
  • 期号:7
  • 页码:1455-1465
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Studies were conducted to determine whether pectin (PE) or psyllium (PSY) could reverse the high plasma cholesterol and triacylglycerol (TAG) concentrations induced by high fat (HF) or high sucrose (HS) diets and which are the mechanisms involved. Male guinea pigs were fed either a low fat (LF) or a HF diet with 80% of the carbohydrate energy derived from sucrose. Cellulose was used as control. Plasma LDL cholesterol, TAG, apolipoprotein B, and hepatic cholesteryl ester were lower in guinea pigs fed PE and PSY compared to the control group ( P P P ApoB secretion was reduced by pectin and psyllium ( P J. Lipid Res. 1998. 39: 1455–1465.
  • 关键词:pectin ; psyllium ; dietary fat amount ; sucrose ; apoB/E receptor ; HMG-CoA reductase ; cholesterol 7α-hydroxylase ; guinea pig
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