出版社：American Society for Biochemistry and Molecular Biology
摘要：The effect of replacing dietary choline with dimethylaminoethanol and dimethylamino iso propyl alcohol on the larval phospholipids of the blowfly Phormia regina was investigated. It was found that these compounds were incorporated into the phospholipids to the extent of approximately 30% of the total phospholipids when dimethylaminoethanol was used and approximately 18% when dimethylamino iso propyl alcohol was added to the diet. The separation of these phospholipids by silicic acid chromatography followed by chromatography on DEAE-cellulose is described. The amount of phospholipid-bound choline was greatly reduced when either of these two compounds was incorporated into the phosphatides. The possible significance of these findings is discussed.
