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  • 标题:Lipoprotein lipase genetics, lipid uptake, and regulation
  • 本地全文:下载
  • 作者:Martin Merkel ; Robert H. Eckel ; Ira J. Goldberg
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:2002
  • 卷号:43
  • 期号:12
  • 页码:1997-2006
  • DOI:10.1194/jlr.R200015-JLR200
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:Lipoprotein lipase (LPL) regulates the plasma levels of triglyceride and HDL. Three aspects are reviewed. 1 ) Clinical implications of human LPL gene variations: common mutations and their effects on plasma lipids and coronary heart disease are discussed. 2 ) LPL actions in the nervous system, liver, and heart: the discussion focuses on LPL and tissue lipid uptake. 3 ) LPL gene regulation: the LPL promoter and its regulatory elements are described.
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