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  • 标题:Measurement of fasting serum apoB-48 levels in normolipidemic and hyperlipidemic subjects by ELISA
  • 本地全文:下载
  • 作者:Naohiko Sakai ; Yoshiaki Uchida ; Koji Ohashi
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:2003
  • 卷号:44
  • 期号:6
  • 页码:1256-1262
  • DOI:10.1194/jlr.M300090-JLR200
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:The present study was designed to evaluate the metabolism of chylomicron and chylomicron remnants by measuring serum apolipoprotein B-48 (apoB-48) levels in 335 normolipidemic and 253 hyperlipidemic subjects using a novel ELISA system. The distribution of fasting serum apoB-48 levels in normolipidemic subjects varied widely, ranging from 24 μg/ml (mean, 5.2 ± 3.8 μg/ml; median, 3.9 μg/ml). Serum apoB-48 levels correlated with serum triglyceride (TG) concentrations ( r = 0.45, P Our results indicate that serum apoB-48 is a very useful parameter for evaluating lipoprotein metabolism in exogenous pathways.
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