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  • 标题:Apolipoprotein A-I, A-II, and VLDL-B-100 metabolism in men comparison of a low-fat diet and a high-monounsaturated fatty acid diet
  • 本地全文:下载
  • 作者:Sophie Desroches ; Marie-Eve Paradis ; Mélanie Pérusse
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:2004
  • 卷号:45
  • 期号:12
  • 页码:2331-2338
  • DOI:10.1194/jlr.M400287-JLR200
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:The impact of a low-fat diet and a high-MUFA diet on apolipoprotein A-I (apoA-I), apoA-II, and VLDL-apoB-100 metabolism in conditions of unrestricted (ad libitum) energy intake was compared in 65 men randomly assigned to one of two predefined experimental diets. A subsample of 18 men participated in the kinetic study. Before and after the 6–7 week dietary intervention, kinetic subjects received a primed-constant infusion of [5,5,5-2H3] l -leucine for 12 h under feeding conditions. ApoA-I production rate (PR; −31.5%; P P P P These results emphasize the differential impact of the low-fat diet and high-MUFA diet on HDL metabolism.
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