出版社:American Society for Biochemistry and Molecular Biology
摘要:The impact of a low-fat diet and a high-MUFA diet on apolipoprotein A-I (apoA-I), apoA-II, and VLDL-apoB-100 metabolism in conditions of unrestricted (ad libitum) energy intake was compared in 65 men randomly assigned to one of two predefined experimental diets. A subsample of 18 men participated in the kinetic study. Before and after the 6–7 week dietary intervention, kinetic subjects received a primed-constant infusion of [5,5,5-2H3] l -leucine for 12 h under feeding conditions. ApoA-I production rate (PR; −31.5%; P P P P These results emphasize the differential impact of the low-fat diet and high-MUFA diet on HDL metabolism.