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  • 标题:Xanthophylls are preferentially taken up compared with β-carotene by retinal cells via a SRBI-dependent mechanism,
  • 本地全文:下载
  • 作者:Alexandrine During ; Sundari Doraiswamy ; Earl H. Harrison
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:2008
  • 卷号:49
  • 期号:8
  • 页码:1715-1724
  • DOI:10.1194/jlr.M700580-JLR200
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:The purpose of this study was to investigate the mechanisms by which carotenoids [xanthophylls vs. β-carotene(β-C)] are taken up by retinal pigment epithelial (RPE) cells. The human RPE cell line, ARPE-19, was used. When ARPE-19 cells were fully differentiated (7–9 weeks), the xanthophylls lutein (LUT) and zeaxanthin (ZEA) were taken up by cells to an extent 2-fold higher than β-C ( P
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