出版社：American Society for Biochemistry and Molecular Biology
摘要：Inflammation has been proposed to impair HDL function and reverse cholesterol transport (RCT). We investigated the effects of inflammation mediated by zymosan, a yeast glucan, on multiple steps along the RCT pathway in vivo and ex vivo. Acute inflammation with 70 mg/kg zymosan impaired RCT to plasma, liver, and feces similarly by 17–22% ( P P P P
关键词：high density lipoprotein ; cholesterol efflux ; macrophages
