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  • 标题:Effect of fenofibrate and atorvastatin on VLDL apoE metabolism in men with the metabolic syndrome
  • 本地全文:下载
  • 作者:Esther M. M. Ooi ; Theodore W. K. Ng ; Gerald F. Watts
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:2012
  • 卷号:53
  • 期号:11
  • 页码:2443-2449
  • DOI:10.1194/jlr.P029223
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:We examined the effects of fenofibrate and atorvastatin on very low density lipoprotein (VLDL) apolipoprotein (apo)E metabolism in the metabolic syndrome (MetS). We studied 11 MetS men in a randomized, double-blind, crossover trial. VLDL-apoE kinetics were examined using stable isotope methods and compartmental modeling. Compared with placebo, fenofibrate (200 mg/day) and atorvastatin (40 mg/day) decreased plasma apoE concentrations ( P P P P
  • 关键词:apolipoprotein E ; lipoprotein metabolism ; statin ; very low density lipoprotein
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