出版社:American Society for Biochemistry and Molecular Biology
摘要:The trisubstituted cholanoic acids in human feces have been studied by gas chromatography-mass spectrometry. The following bile acids have been identified: 3β,7α,12α-trihydroxy-, 3β,7β,12α-trihydroxy-, 3α,7α-dihydroxy-12-keto-5β-cholanoic acids and 3α,7α,12α-trihydroxy-5α-cholanoic acid. The presence in human feces of 3α,7α,12α-trihydroxy-, 3α,7β,12α-trihydroxy-, and 3α,12α-dihydroxy-7-keto-5β-cholanoic acids has been confirmed. The composition of bile acids in human feces is summarized and possible metabolic interrelationships suggested.