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  • 标题:Hypocholesterolemic activity of 17α-methyl-5α-androstane-3β,17β-diol, a metabolite of 17α-methyltestosterone
  • 本地全文:下载
  • 作者:Liese L. Abell ; Erwin H. Mosbach
  • 期刊名称:JLR Papers In Press
  • 印刷版ISSN:0022-2275
  • 电子版ISSN:1539-7262
  • 出版年度:1968
  • 卷号:9
  • 期号:1
  • 页码:98-102
  • 语种:English
  • 出版社:American Society for Biochemistry and Molecular Biology
  • 摘要:The hypocholesterolemic activities of 17amethyltestosterone and its major identified fecal metabolite, 17α-methyl-5α-androstane-3β,17β-diol, were compared in dogs. The dose-response curves indicated that the two compounds had similar effects, although at doses below 1 mg/kg per day the diol appeared to be more active than the parent compound.
  • 关键词:17α-methyltestosterone ; 17α-methyl-5α-androstane-3β,17β-diol ; hypocholesterolemic agent ; dog ; serum cholesterol ; serum lipoprotein
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