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  • 标题:Studies on Antifungal Activity and Brine Shrimp Toxicity Argemone mexicana
  • 本地全文:下载
  • 作者:Ainun Nahar ; Anwar Habib ; MA Awal
  • 期刊名称:KYAMC Journal
  • 印刷版ISSN:2308-2860
  • 出版年度:2014
  • 卷号:4
  • 期号:2
  • 页码:402-405
  • 语种:English
  • 出版社:Khwaja Yunus Ali Medical College and Hospital
  • 摘要:The present study determined the antifungal activity of the root of extracts Argemone mexicana against 7 fungi using dichloromethane and methanol as solvent. Among these pathogens, 3 were dermatophytes and the rest 4 were nondermatophytes. The dichloromethane extract of Argemone mexicana exhibited moderate to good activity at concentration of 200 μg/disc but at concentration of 50 μg/disc, the same extract showed no activity against the tested fungi. The methanol extract were also inactive against the tested pathogens. In brine shrimp toxicity test, it was observed that LC50 value of the dichloromethane extract of Argemone mexicana was 22.35 μg/ml. From these findings it is indicative that dichloromethane extract of Argemone mexicana is biologically active and may have antifungal principles that could be useful in fungal diseases. KYAMC Journal Vol. 4, No.-2, Jan 2014, Page 402-405
  • 关键词:Argemone mexicana;Antifungal activity;Brine shrimp toxicity
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