The objective of research is to describe the knowledge and attitude of basic sanitation management community in Kupang City. This type of research is a survey research using quantitative approach. Data were collected by using the instrument in the form of test knowledge of basic sanitation management and attitude questionnaire. The data was then processed and analyzed using descriptive statistics. The Result of the research was sanitation management knowledge base is in low category whereas attitude clean and healthy life, about 61.5% of Kupang not leave a comment. The knowledge is still low is illustrated by the habit of living of the community, particularly in watersheds where there are many people using the river as a final disposal of feces them also as a public bathing and washing.