Setting greenhouse gas emission target is a critical step to meet the challenge of climate change. While the debate on global and national carbon emission targets has dominated every major climate change conference, little is known about how the firms set emission targets. Using a dataset on S&P 500 companies in the United States, we investigate the determinants of firm-level climate change mitigation targets, including target adoption and target metric (intensity target vs. absolute target). We find that companies with larger size, higher growth, better innovation, weaker capital constraint, and higher government pressure are more likely to establish emission targets. Further, firm growth has a negative (positive) and significant association with the use of absolute (intensity) target. This may be due to the fact that intensity target can better accommodate growth than absolute target. Policymakers and corporate managers may resort to those determinant factors in designing climate change policies to induce desirable firm-level target-setting behaviors.