出版社：National Institute of Occupational Safety and Health
摘要：To obtain basic data on TLV for toluene and early findings of toluene intoxica-tion, some investigations were undertaken for female shoe makers exposed to low concentration of toluene vapor ranging about 60 to 100 ppm. Subjective symptoms of the exposed group were significantly different from those of control group on sensation of general weakness, dysmenorrhoea, itching and dermatitis of hands and feeling uneasy about solvent vapor. In hematological findings, there was no significant difference in both groups except for appearance rate of Mommsen's toxic granules in peripheral neutrophiles. Mean value and standard deviation of hippuric acid concentration in the urine were 3.26±0.82mg/m l in ex-posed group and 0.35±0.24mg/m l in control group, which revised at 1.024 by specific gravity. There were some significant differences between them in neurologic and muscular function tests such as abnormal tendon reflex, grasping power of not-dominant in the whip hand, decrease in tapping tempo, agility of the fingers, and so forth. These findings suggest that TLV of 100 ppm for toluene adopted in Japan As-sociation of Industrial Health should be reconsidered.
