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  • 标题:Cytotoxic Activities of Solanum Steroidal Glycosides
  • 本地全文:下载
  • 作者:Takanori NAKAMURA ; Chieko KOMORI ; Yun-yun LEE
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1996
  • 卷号:19
  • 期号:4
  • 页码:564-566
  • DOI:10.1248/bpb.19.564
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Cytotoxic activities of 20 steroidal glucosides obtained from Solanum genera plants were examined against various cell lines to provide new evidence as follows : 1) As regarding the sugar linkage, the glucosides possessing a β-chacotriosyl moiety were the most effective and the presence of the terminal rhamnosyl residue was required for exhibiting strong activity. 2) As for the aglycone, the glycosides carrying a spirostanol aglycone showed the strongest activity and even an aglycone without a sugar linkage presented considerably strong activity.
  • 关键词:cytotoxic activity;Solanum alkaloid;steroidal glycoside;β-chacotriosyl moiety
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