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  • 标题:3-Deoxyglucosone Reductase in Dog Adrenal Glands. Identification as Aldose Reductase
  • 本地全文:下载
  • 作者:Kazuya MATSUURA ; Kumiko SATO ; Yoshihiro DEYASHIKI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1995
  • 卷号:18
  • 期号:12
  • 页码:1765-1767
  • DOI:10.1248/bpb.18.1765
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:3-Deoxyglucosone is one of the major cytotoxic intermediates in the Maillard reaction. Adrenal glands showed the highest NADPH-linked 3-deoxyglucosone reductase activity of dog tissues. The enzyme was purified to homogeneity from the adrenal glands, and demonstrated to be structurally, functionally and immunologically identical with aldose reductase, which comprises about 6% of the soluble adrenal proteins.
  • 关键词:adrenal gland;aldose reductase;3-deoxyglucosone;glycation;β-keto acid ester
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