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  • 标题:In Vitro Effect of Penetration Enhancers on Sodium Nonivamide Acetate in Rat Skin
  • 本地全文:下载
  • 作者:Pao-Chu WU ; Jia-You FANG ; Yaw-Bin HUANG
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1995
  • 卷号:18
  • 期号:12
  • 页码:1790-1792
  • DOI:10.1248/bpb.18.1790
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Sodium nonivamide acetate (SNA) is a newly synthetic analogue of capsaicin which produces no overt pungent sensation or irritation. In this present study, the effects and roles of penetration enhancers for SNA through rat skin were investigated by in vitro skin penetration experiment and differential scanning calorimeter (DSC) determination. The penetration fluxes of SNA after the incorporation of enhancers increased in the order of Polysorbate 20
  • 关键词:sodium nonivamide acetate;percutaneous absorption;in vitro;enhancer;differential scanning calorimetry
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