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  • 标题:The Inhibitory Effect of Sulfated Schizophyllans and Related Oligosaccharides on Coagulation and Fibrinolysis
  • 本地全文:下载
  • 作者:Akio HIRATA ; Yoko NAGAMATSU ; Wataru ITOH
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1994
  • 卷号:17
  • 期号:5
  • 页码:739-741
  • DOI:10.1248/bpb.17.739
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Sulfated schizophyllans and sulfated oligosaccharides were prepared and their inhibitory effects on coagulation and fibrinolysis were examined. Some sulfated schizophyllans, which had a sulfur content of more than 10%, prolonged prothrombin time (PT) and thrombin time (TT). Interestingly, some sulfated schizophyllans and related oligosaccharides were able to inhibit plasmin toward fibrinolysis and amidolysis.
  • 关键词:sulfated schizophyllan;sulfated oligosaccharide;inhibitory activity;plasmin;fibrinolysis;coagulation
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