首页    期刊浏览 2024年07月06日 星期六
登录注册

文章基本信息

  • 标题:Production of LLU-α Following an Oral Administration of γ-Tocotrienol or γ-Tocopherol to Rats
  • 本地全文:下载
  • 作者:Akihiro HATTORI ; Takeshi FUKUSHIMA ; Hiroyuki YOSHIMURA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2000
  • 卷号:23
  • 期号:11
  • 页码:1395-1397
  • DOI:10.1248/bpb.23.1395
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:An oral administration of γ-tocotrienol (γ-T3) or γ-tocopherol (γ-Toc) to male rats caused an increase of the concentration of 2, 7, 8-trimethyl-2-(β-carboxyethyl)-6-hydroxy chroman (LLU-α, γ-CEHC), a natriuretic compound, in plasma with a Tmax of 9 h. The configuration at C-2 of LLU-α produced from γ-T3 or γ-Toc was assigned as S-form by an HPLC equipped with a chiral column. These data indicated that LLU-α was produced not only from γ-Toc but also γ-T3, without racemization at C-2 in rats.
  • 关键词:LLU-α(γ-CEHC);γ-tocotrienol;γ-tocopherol;rat plasma;HPLC
国家哲学社会科学文献中心版权所有