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  • 标题:Biopolymers from Marine Invertebrates. XIV. Antifungal Property of Dolabellanin A, a Putative Self-Defense Molecule of the Sea Hare, Dolabella auricularia
  • 本地全文:下载
  • 作者:Ryosuki IIJIMA ; Jun KISUGI ; Masatoshi YAMAZAKI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1994
  • 卷号:17
  • 期号:8
  • 页码:1144-1146
  • DOI:10.1248/bpb.17.1144
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Dolabellanin A (DAA), the antineoplastic and antibacterial glycoprotein purified from the albumen gland of Dolabella auricularia, showed an antifungal activity. DAA suppressed fungal growth completely at a concentration of over 2μg/ml, and the colony forming ability of the fungus was significantly decreased after contact with DAA. These results indicate that DAA is an antifungal protein and its mode of antifungal activity is fungicidal.
  • 关键词:antifungal protein;antineoplastic protein;marine animal;sea hare;Dolabella auricularia;dolabellanin A
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