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  • 标题:Effects of Du-Zhong Leaf Extract on Serum and Hepatic Lipids in Rats Fed a High-Fat Diet
  • 本地全文:下载
  • 作者:Koichi METORI ; Sigeki OHASHI ; Shushichi TAKAHASHI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1994
  • 卷号:17
  • 期号:7
  • 页码:917-920
  • DOI:10.1248/bpb.17.917
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:We evaluated the effects of Du-Zhong leaf extract on the serum and liver lipids in rats fed a high-fat diet supplemented with animal fat, cholesterol and cholate. The Du-Zhong leaf extract suppressed significantly the high-fat diet-induced increases in total serum cholesterol, serum triacylglycerol and hepatic triacylglycerol but not the total hepatic cholesterol. The Du-Zhong leaf extract also suppressed the high-fat diet induced increases in very-low density lipoprotein and low density lipoprotein without affecting high density lipoprotein cholesterol. These results suggest that Du-Zhong leaf extract may be beneficial for the regulation of hyperlipidemia.
  • 关键词:cholesterol;triacylglycerol;Eucomia ulmoides;high-fat diet (HFD);lipid metabolism;rat
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