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  • 标题:A Glucan with Immunological Activities from the Tuber of Alisma orientale
  • 本地全文:下载
  • 作者:Noriko SHIMIZU ; Sadanori OHTSU ; Masashi TOMODA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1994
  • 卷号:17
  • 期号:12
  • 页码:1666-1668
  • DOI:10.1248/bpb.17.1666
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:A glucan, called alisman SI, was isolated from the tuber of Alisma orientale JUZEPCZ. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was 1.1×104. It is composed solely of D-glucose. Methylation analysis, nuclear magnetic resonance and enzymic degradation studies indicated that it has a high-branched glucan type structure mainly composed of α-1, 4-linked D-glucopyranosyl residues with partially α-1, 6-linked units and both 3, 4- and 4, 6-branching points. The polysaccharide exhibited significant reticuloendothelial system-potentiating activity in a carbon clearance test, as well as a pronounced anti-complementary activity.
  • 关键词:glucan;polysaccharide structure;immunological activity;Alisma orientale;alisman SI;tuber
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