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  • 标题:ATOMIC FORCE MICROSCOPY OF DIMYRISTOYLPHOSPHATIDYLCHOLINE MEMBRANES
  • 本地全文:下载
  • 作者:Yukio SATO ; Zhansong CHEN ; Takeo TAKAHASHI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1994
  • 卷号:17
  • 期号:12
  • 页码:1682-1685
  • DOI:10.1248/bpb.17.1682
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:We have observed the surface images of dimyristoylphosphatidylcholine (DMPC) monolayer and DMPC vesicles with an atomic force microscope (AFM). It was confirmed that the lattice structure of polar head groups of DMPC molecules in a Langmuir-Blodgett monolayer is similar to those of large unilamellar DMPC vesicles. AFM images of small unilamellar vesicles of DMPC showed larger lattice structures than those of the monolayer, reflecting differences of molecular packing in these membranes.
  • 关键词:atomic force microscope;dimyristoylphosphatidylcholine;Langmuir-Blodgett film;small unilamellar vesicle;lattice structure
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