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  • 标题:Disposition of Enantiomers of sultopride in a Human, Rats and Rabbits
  • 本地全文:下载
  • 作者:Ayako KAMIZONO ; Nobuo INOTSUME ; Syouji FUKUSHIMA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1993
  • 卷号:16
  • 期号:11
  • 页码:1121-1123
  • DOI:10.1248/bpb.16.1121
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Pharmacokinetics of sultopride enantiomers was examined following a single dose in a human, rabbits and rats. Pharmacokinetic profiles were similar between (+)- and (-)-enantiomers of sultopride in human, whereas the serum concentrations of (-)-sultopride were slightly higher than those of (+)-sultopride after i.v. administration of 50 mg/kg of racemic sultopride to rats and rabbits.
  • 关键词:sultopride;enantiomer;stereoselective disposition;human;rat;rabbit
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