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  • 标题:Trypanocidal Effects of Curcumin in Vitro
  • 本地全文:下载
  • 作者:Mitsuhiko NOSE ; Tatsuo KOIDE ; Yukio OGIHARA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1998
  • 卷号:21
  • 期号:6
  • 页码:643-645
  • DOI:10.1248/bpb.21.643
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:During the course of study searching for the antiparasitic agents from natural compounds, we found that curcumin showed cytotoxicity against African trypanosomes in vitro. The LD50 values of curcumin were 4.77±0.91μM for bloodstream forms and 46.52±4.94μM for procyclic forms of Trypanosoma brucei brucei (GUTat 3.1 clone).
  • 关键词:curcumin;Trypanosoma brucei brucei (GUTat 3.1);trypanocidal activity
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