摘要：A cross-sectional study to assess the associations between lifestyle factors and cancer risk was conducted in five areas of Japan (Ninohe in Iwate, Yokote in Akita, Katsushika-kita in Tokyo, Saku in Nagano and Ishikawa in Okinawa) with different cancer mortality patterns. The subjects were randomly selected men aged 40 to 49 years and their spouses, and they all volunteered to participate in this study. The study included a questionnaire on lifestyle performed by interview, a health check-up and sampling of blood and urine. Furthermore, a 24-hour urine collection and 3-day nutritional survey were added as supplementary items. The overall participation rate was 72% (634/880) : 77% in Ninohe, 78% in Yokote, 61% in Katsushika-kita, 71% in Saku, and 76% in Ishikawa. The wives of 59% (373/634) of the male participants also entered the study. A 24-hour urine collection and 3-day nutritional survey were also conducted in about one third of the participants. Profiles of participants revealed significant differences among each study area, such as length of residence, marital status, and occupation. J Epidemiol, 1992; 2 : 75-81.
