摘要：Changes in neurotransmission are known to take place in a variety of conditions, such as Parkinson's disease, A neurofilament-deficient mutant of the Japanese quail, named the Quiver quail, exhibits generalized quivering as a clinical sign. The content of monoamines (noradrenaline (NA), dopamine and 5-hydroxytryptamine) and the uptake and release of L-[3H]NA were measured in brain of this bird. In Quiver, the NA content in neostriatum and thalamus, and the 5-hydroxytryptamine content in neostriatum, paleostraitum and thalamus were significantly increased, in comparison with the normal quail. The dopamine content and L-[3H]NA uptake and release in the Quiver mutant were similar to those in normal quail.
