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  • 标题:Reaction of Malondialdehyde (MDA) with α-N-Acetylhistidine in the Presence of Alkanal
  • 本地全文:下载
  • 作者:Takeshi OHYA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1994
  • 卷号:17
  • 期号:4
  • 页码:554-556
  • DOI:10.1248/bpb.17.554
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The reaction of malondialdehyde (MDA) with α-N-acetyl-histidine (Ac-His) in the presence of alkanal was investigated. MDA alone did not react with Ac-His but when alkanal was present, a reaction took place. A similar result was obtained for the reaction of MDA with imidazole in the presence of alkanal. In addition, the structure of the product obtained following the reaction of MDA with imidazole in the presence of acetaldehyde was investigated. The structure of this product was identified as a 1 : 1 : 1 adduct of MDA, acetaldehyde and imidazole (2).
  • 关键词:malondialdehyde;α-N-acetyhistidine;imidazole;acetaldehyde;alkanal
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