标题：Effects of Voluntary Running Exercise on Blood Pressure and Renin-Angiotensin System in Spontaneously Hypertensive Rats and Normotensive Wistar-Kyoto Rats
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2000
卷号：46
期号：4
页码：165-170
DOI：10.3177/jnsv.46.165
出版社：Center for Academic Publications Japan
摘要：The effect of a voluntary running exercise on blood pressure and renin-an-giotensin system (RAS) Was studied in male spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY). SHR and WKY Were assigned to either voluntary running exercise or sedentary control groups at 5 wk of age. The systolic blood pressure in the exercised group for both strains of rats was significantly lower than in the sedentary control group. The plasma renin activity (PRA) and plasma renin concentration (PRC) were significantly lower in voluntary running exercised SHR than in sedentary SHR, whereas the same exercise did not result in a lower PRA and PRC in WKY. These results suggested that the blood pressure lowering effect of voluntary running exercise is related to the suppres-sion of RAS in SHR.
