期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2000
卷号：46
期号：3
页码：115-118
DOI：10.3177/jnsv.46.115
出版社：Center for Academic Publications Japan
摘要：Vitamin D deficiency has been reported to result in impaired glucose tolerance and decreased insulin secretion when glucose is administered either intravenously or in-traperitoneally. The aim of the present study was to study oral glucose tolerance and glucose absorption in a vitamin D-deficient rat model, Oral glucose tolerance tests were carried out in vitamin D-deficient and control rats, and this was found to be unaltered in the deficient state. Intestinal absorption of glucose was drastically reduced in the deficient animal and was found to be due to a reduction in the sodium-dependent component of glucose trans-port. Thus the unaltered oral glucose tolerance in the vitamin D-deficient rat is probably due to impaired absorption of glucose.
关键词：25-OH-D3;vitamin D deficiency;glucose tolerance;glucose absorption
