期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2000
卷号：46
期号：3
页码：119-124
DOI：10.3177/jnsv.46.119
出版社：Center for Academic Publications Japan
摘要：The purpose of this study was to investigate the change in vitamin E level in both serum and red blood cells (RBC) during exercise and to clarify the effect of vitamin E supplementation. Ten young sedentary female subjects received 200mg D-α-tocopherol ac-etate daily for 1 wk after the initial exercise bout. After 1 wk of vitamin E supplementation, the same subjects repeated the same exercise. Before vitamin E supplementation, the α-tocopherol level in the serum (serum-α-tocopherol) did not change after exercise, but a signif-icant decrease in the α-tocopherol level in RBC (RBC-α-tocopherol) was observed after exer-cise ( p <0.05). On the other hand, after vitamin E supplementation, the serum-α-toco-pherol level decreased significantly after exercise ( p <0.05), while the RBC-α-tocopherol level was maintained after exercise. Furthermore, a negative correlation between the changes in serum- and RBC-a-tocopherol levels was observed only after vitamin E supple-mentation ( r =0.667, p <0.05). The present results suggest that as RBC suffers oxidative stress, vitamin E in RBC is consumed to protect RBC from oxidative damage during exercise. These results also suggest that when there is a sufficient amount of vitamin E in the serum, vitamin E is shifted from the serum to RBC, resulting in a steady RBC-α-tocopherol level and a decrease in the serum-α-tocopherol level under oxidative stress such as exercise.
关键词：α-tocopherol;exercise;vitamin E supplementation;oxidative stress;red blood cells
