出版社：National Institute of Occupational Safety and Health
摘要：Using a fluorometric HPLC method, we determined δ-aminolevulinic acid (ALA) in sera and urine samples from 16 lead workers with blood lead levels ranging from 19 to 107 μG/100 ml. The concentration of ALA in serum correlated highly with the urinary ALA concentration (γ=0.957 for ALA mg/1, γ=0.967 for ALA mg/g creatinine). The ALA concentrations in the serum of lead workers ranged from 11 to 151 μg/1 with a mean of 51 μg/1. In addition, the concentrations of urinary ALA (mg/g creatinine) and serum ALA μg/1) had a strong correlation with blood lead concentrations (γ=0.838 and 0.892, respectively). These data indicate that the measurement of serum ALA, as well as urinary ALA, is very useful for the biological monitoring of occupational lead exposure.
关键词：Lead exposure;δ-Aminolevulinic acid;Urine;Serum;Blood lead
