出版社:National Institute of Occupational Safety and Health
摘要:Effect of manganese administration, on the morphology and metal concentration in various tissues of rats fed 10% casein diet, were investigated. Daily intra-peritoneal administration of MnC12•H2O (15 mg/kg) to the rats fed 10% casein diet for a period of 45 days produced almost identical increase in metal concentration of various tissues as after similar treatment to the animals fed basal diet. Protein deficient diet did not alter the extent of manganese induced morphological lesions in various tissues of rats. The data indicated that 10% casein diet to the adult rats did not make them more susceptible to manganese poisoning.