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  • 标题:EXPERIMENTAL STUDY ON CONTACT DERMATITIS CAUSED BY FUNGICIDES BENOMYL AND THIOPHANATE-METHYL
  • 本地全文:下载
  • 作者:Toshio MATSUSHITA ; Mitsuki YOSHIOKA ; Koji AOYAMA
  • 期刊名称:Industrial Health
  • 印刷版ISSN:0019-8366
  • 电子版ISSN:1880-8026
  • 出版年度:1977
  • 卷号:15
  • 期号:3-4
  • 页码:141-147
  • DOI:10.2486/indhealth.15.141
  • 出版社:National Institute of Occupational Safety and Health
  • 摘要:Though primary irritancy was not indicated for fungicides benomyl and thiophanate-methyl, extreme potency of contact sensitization was estimated only for benomyl from the guinea pig maximization test. Allergenicity ratings of sulfuric compounds, lime sulfur mixture and wettable sulfur powder, and a portion of chemical structure for benomyl, i.e., n-butyl carbamate were noted to be moderate, but such degree of allergenicity was not observed in cases of thiophanate-methyl and one of their metabolite MBC. Contact sensitization for thiophanate-methyl, however, seemed to be potentiate slightly when used with a sulfuric compound. The cross sensitization between benomyl and thiophanate-methyl was not revealed.
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