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  • 标题:Estimation of the Lethal Toluene Concentration from the Accidental Death of Painting Workers
  • 本地全文:下载
  • 作者:Tatsuya HOBARA ; Masayuki OKUDA ; Masayuki GOTOH
  • 期刊名称:Industrial Health
  • 印刷版ISSN:0019-8366
  • 电子版ISSN:1880-8026
  • 出版年度:2000
  • 卷号:38
  • 期号:2
  • 页码:228-231
  • DOI:10.2486/indhealth.38.228
  • 出版社:National Institute of Occupational Safety and Health
  • 摘要:To determine the potentially lethal level of thinner concentration in the air, we measured the concentration of toluene in the blood and others of three patients who suffered severe acute thinner intoxication between 4 January 1996 and 21 April 1997 in Ube city. The concentration of toluene in blood were 30.2mg/L in died patient, and 13.7mg/L and 17.5mg/L in recovered patients, respectively. By extrapolation from the results of our previous toxicokinetic reseach on toluene poisoning in anesthetized dogs, the fatal concentration of toluene was estimated to be approximately 1800 to 2000 ppm for 1-hour exposure.
  • 关键词:Toluene;Lethal concentration;Toxicokinetics;Hippuric acid
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