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  • 标题:Urinary Metabolites of Daidzin Orally Administered in Rats
  • 本地全文:下载
  • 作者:Takaaki YASUDA ; Keisuke OHSAWA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1998
  • 卷号:21
  • 期号:9
  • 页码:953-957
  • DOI:10.1248/bpb.21.953
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:In a study on teh metabolism of flavonoids, the isoflavone glycoside daidzin was orally administered to rats. Urine samples were collected and treated with β-glucuronidase and arylsulfatase. Aglycone daidzein (M3) and other three metaboliters, 3', 4', 7-trihydroxyisoflavone (M1), 4', 7-dihydroxyisoflavanone (M2) and 4', 7-dihydroxyisoflavan (M4) were isolatd from the urine following treatment with enzymes. The structures of M1, M2 and M4 were determined on the basis of chemical and spectral data.
  • 关键词:daidzin;Puerariae lobata OHWI;urinary metabolite;3', 4', 7-trihydroxyisoflavone;4', 7-dihydroxyisoflavanone;equol
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