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  • 标题:Anti-Helicobacter pylori Activity of Hearbal Medicines
  • 本地全文:下载
  • 作者:Eun-Ah BAE ; Myung Joo HAN ; Nam-Jae KIM
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1998
  • 卷号:21
  • 期号:9
  • 页码:990-992
  • DOI:10.1248/bpb.21.990
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The extracts of Coptidis japonica (rhizoma), Eugenia caryophyllata (flower), Rheum palmatum (rhizoma), Magnolia officinalis (cortex) and Rhus javanica (galla rhois) potently inhibited the grow of Helicobacter pylori (HP). However, these herbal extracts showed no inhibitory effect on HP urease except Galla rhois. Among the components separated from active herbal extracts by silica gel column chromatography, the inhibitory effects of decursinal angelate and decursion on the growth of HP were the most potent, followed by magnolol, berberine, cinnamic acid, decursinol and gallic acid. Minimum inhibitory concentrations (MICs) of decursin and decursinol anglate were 6-20 μg/ml
  • 关键词:Helicobacter pylori;Angelica gigas;Coptis japonica;berberine;magnolol;decurcin
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