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  • 标题:Isolation and Identification of Compounds from Brazilian Propolis which Enhance Macrophage Spreading and Mobility
  • 本地全文:下载
  • 作者:Tomoki TATEFUJI ; Noboru IZUMI ; Tsunetaka OHTA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1996
  • 卷号:19
  • 期号:7
  • 页码:966-970
  • DOI:10.1248/bpb.19.966
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Brazilian propolis is known to induce the activation of murine effector cells. We isolated and identified six compounds from a water-soluble extract of Brazilian propolis, all of which have enhancing effects on the spreading and mobility of murine macrophages. These compounds were identified as caffeoylquinic acid-derivatives, namely, 5-caffeoylquinic acid (1), chlorogenic acid (2), 4-caffeoylquinic acid (3), 4, 5-dicaffeoylquinic acid (4), 3, 5-dicaffeoyquinic acid (5) and 3, 4-dicaffeoylquinic acid (6).
  • 关键词:propolis;caffeoylquinic acid;macrophage;spreading;mobility;Brazil
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