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  • 标题:CALCEIN RELEASE FROM TEMPERATURE-SENSITIVE LIPOSOME WITH OR WITHOUT STIRRING
  • 本地全文:下载
  • 作者:Atsuo ONO ; Masaaki YAMAGUCHI ; Isamu HORIKOSHI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1994
  • 卷号:17
  • 期号:1
  • 页码:166-168
  • DOI:10.1248/bpb.17.166
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Characteristics of the calcein release from temperature-sensitive liposomes with or without stirring were studied. Calcein release from DPPC(dipalmitoylphosphatidylcholine) REV(reverse phase evaporation vesicle) with stirring occurred at a temperature lower by 8 degrees than that without stirring. DPPC-DSPC(distearoylphasphatidylcholine)-mixed REV showed the maximum release(%) for calcein, near 40 °C with stirring and 45 °C without stirring.
  • 关键词:temperature-sensitive;with stirring;liposome;drug release
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