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  • 标题:Inhibitory Effects of Tannins on NADH Dehydrogenases of Various Organisms
  • 本地全文:下载
  • 作者:Kiyoshi KONISHI ; Hirokazu ADACHI ; Naoko ISHIGAKI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1993
  • 卷号:16
  • 期号:7
  • 页码:716-718
  • DOI:10.1248/bpb.16.716
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:We examined the effects of purified tannins and related compounds (33 species) on NADH-ubiquinone-1 oxidoreductase activity in four kinds of organism (Paracoccus denitrificans, Bacillus subtilis, Photobacterium phosphoreum, and Thermus thermophilus HB-8) and rat liver mitochondria. In addition to pentagalloylglucose, which was reported as a potent inhibitor of NADH dehydrogenases (NDH), sanguiin H-11, oolonghomobisflavan A, and polymerized procyanidin are potent inhibitors for both types of NDH (NDH-1 and NDH-2). We found that some other tannins contained in tea are also inhibitors of NDH from all organisms.
  • 关键词:NADH dehydrogenase;respiratory chain;tannin;mitochondria;bacteria
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